John R Spratt

John R Spratt, MD

Clinical Assistant Professor

Business Phone: (352) 273-5501
Business Email:

About John R Spratt

My name is John R Spratt, MD, and I am a clinical assistant professor of thoracic and cardiovascular surgery. My inspiration to go into medicine came from my parents; my father is a cardiothoracic surgeon and my mother is a nurse. My decision to become a thoracic and cardiovascular surgeon was solidified during my time as a medical student and general surgery resident, where I participated in the care of critically ill cardiac and thoracic surgical patients.

I treat patients with the full breadth of adult cardiac surgical disease, including coronary artery disease, mitral and aortic valve disease, atrial fibrillation, aortic aneurysm and dissection, and atrial fibrillation. I also have a particular interest in catheter-based valve therapies, including TAVR, TEER, and TMVR, and moderate our weekly multidisciplinary valve conference.

I earned my medical degree from the Medical University of South Carolina. I then completed my residency in general surgery at the University of Minnesota Medical School, where I served as administrative chief resident during my final year. Following my residency, I completed fellowship training in thoracic and cardiovascular surgery at the University of Florida College of Medicine. I am certified by the American Board of Surgery and American Board of Thoracic Surgery.

I am committed to understanding each patient’s specific situation to help them make the best possible decisions about their care. I enjoy reviewing imaging studies, talking to patients and their families, and examining all the possibilities to ensure we make the correct diagnosis and construct an appropriate treatment plan for each patient. My research interests include the use of cerebrospinal fluid drains and other measures used in open and endovascular aortic surgery for the prevention of spinal cord ischemia.

Outside of work I enjoy reading, exercising, and spending time with my wife, Claire. Our hobbies include yoga, Formula 1 racing, cooking, and exploring Florida.

Board Certifications

  • Surgery
    American Board of Surgery
  • Thoracic Surgery
    American Board of Thoracic Surgery

Clinical Profile

  • Thoracic and Cardiovascular Surgery
Areas of Interest
  • Acute coronary syndrome
  • Aortic arch syndrome
  • Aortic dissection
  • Aortic regurgitation
  • Aortic stenosis
  • Aortic valve surgery – minimally invasive
  • Aortic valve surgery – open
  • Atrial fibrillation or flutter
  • Bicuspid aortic valve
  • Coronary artery spasm
  • Coronary heart disease
  • Extracorporeal membrane oxygenation (ECMO)
  • Heart bypass surgery
  • Heart valve surgery
  • Mitral regurgitation – acute
  • Mitral stenosis
  • Mitral valve prolapse
  • Mitral valve regurgitation
  • Mitral valve surgery – open
  • Open heart surgery
  • Thoracic aortic aneurysm
  • Thoracic aortic aneurysm (TAA)
  • Thoracoabdominal Aortic Aneurysm
  • Transcatheter aortic valve replacement
  • Transcatheter aortic valve replacement (TAVR)
  • Tricuspid regurgitation
  • Valvular Disease

Research Profile

Open Researcher and Contributor ID (ORCID)


Areas of Interest
  • Prevention of spinal cord ischemia


Aortic Valve Injury During Thoracic Endovascular Aortic Repair Requiring Emergent Surgical Aortic Valve Replacement.
Journal of cardiothoracic and vascular anesthesia. 38(3):792-795 [DOI] 10.1053/j.jvca.2023.11.023. [PMID] 38105125.
Caseous Calcification of the Interventricular Septum Leading to Left Ventricular Outflow Tract Obstruction in the Setting of a Normal Mitral Valve Annulus.
Journal of cardiothoracic and vascular anesthesia. 38(7):1543-1549 [DOI] 10.1053/j.jvca.2024.03.022. [PMID] 38622034.
Perioperative Cerebrospinal Fluid Drain Placement Does Not Increase Venous Thromboembolism Risk After Thoracic and Fenestrated Endovascular Aortic Repair.
Annals of vascular surgery. 99:58-64 [DOI] 10.1016/j.avsg.2023.09.079. [PMID] 37972728.
Rescue therapy for symptomatic spinal cord ischemia after thoracic endovascular aortic repair.
The Journal of thoracic and cardiovascular surgery. 168(1):15-25.e11 [DOI] 10.1016/j.jtcvs.2022.10.045. [PMID] 36509568.
Venoarterial Extracorporeal Membrane Oxygenation for “Protected” Percutaneous Coronary Intervention Secondary to Refractory Polymorphic Ventricular Tachycardia and Cardiac Arrest.
Annals of cardiac anaesthesia. 27(3):246-248 [DOI] 10.4103/aca.aca_136_23. [PMID] 38963360.
A highly penetrant ACTA2 mutation of thoracic aortic disease.
Journal of cardiothoracic surgery. 18(1) [DOI] 10.1186/s13019-023-02420-0. [PMID] 38044429.
Commentary: “Poco a Poco” Thoracic Endovascular Aortic Repair in Uncomplicated Type B Aortic Dissection.
Seminars in thoracic and cardiovascular surgery. 35(2):298-299 [DOI] 10.1053/j.semtcvs.2022.03.005. [PMID] 35339695.
Presentation and Outcomes of Elective and Nonelective Complex Endovascular Repair for Thoracoabdominal and Juxtarenal Aortic Aneurysms.
Annals of vascular surgery. 97:248-256 [DOI] 10.1016/j.avsg.2023.09.001. [PMID] 37714262.
Self-pay insurance status is associated with failure of medical therapy in patients with acute uncomplicated type B aortic dissection.
Surgery. 174(6):1476-1482 [DOI] 10.1016/j.surg.2023.08.003. [PMID] 37718170.
Safety of cerebrospinal fluid drainage for spinal cord ischemia prevention in thoracic endovascular aortic repair.
JTCVS techniques. 14:9-28 [DOI] 10.1016/j.xjtc.2022.05.001. [PMID] 35967198.
Coronary Artery Bypass: Review of Surgical Techniques and Impact on Long-Term Revascularization Outcomes.
Cardiology and therapy. 10(1):89-109 [DOI] 10.1007/s40119-021-00211-z. [PMID] 33515370.
COVID-19 and cardiothoracic surgery: Effects on training and workforce utilization in a global pandemic.
Journal of cardiac surgery. 36(9):3296-3305 [DOI] 10.1111/jocs.15773. [PMID] 34173279.
Prolonged extracorporeal preservation and evaluation of human lungs with portable normothermic ex vivo perfusion
Clinical Transplantation. 34(3) [DOI] 10.1111/ctr.13801.
Transcatheter aortic valve replacement 24 years after cardiac transplantation.
Journal of cardiac surgery. 35(3):710-712 [DOI] 10.1111/jocs.14438. [PMID] 31971286.
Greater survival despite increased complication rates following lung transplant for alpha-1-antitrypsin deficiency compared to chronic obstructive pulmonary disease.
Journal of thoracic disease. 11(4):1130-1144 [DOI] 10.21037/jtd.2019.04.40. [PMID] 31179055.
Impact of 30 Day Readmission After Left Ventricular Assist Device Implantation.
ASAIO journal (American Society for Artificial Internal Organs : 1992). 65(3):252-256 [DOI] 10.1097/MAT.0000000000000812. [PMID] 29750684.
Prospective Trial of Low-Fidelity Deliberate Practice of Aortic and Coronary Anastomoses (TECoG 002)
Journal of Surgical Education. 76(3):844-855 [DOI] 10.1016/j.jsurg.2018.09.007.
Single Versus Bilateral Lung Transplantation for Idiopathic Pulmonary Fibrosis in the Lung Allocation Score Era.
The Journal of surgical research. 234:84-95 [DOI] 10.1016/j.jss.2018.08.054. [PMID] 30527505.
Lung transplant after prolonged ex vivo lung perfusion: predictors of allograft function in swine
Transplant International. 31(12):1405-1417 [DOI] 10.1111/tri.13315.
The ABCs of autologous blood collection for ex vivo organ preservation.
The Journal of thoracic and cardiovascular surgery. 155(1):433-435 [DOI] 10.1016/j.jtcvs.2017.08.036. [PMID] 29129423.
Acute interstitial pneumonitis requiring extracorporeal membrane oxygenation and lung transplantation in an adolescent patient.
The Journal of thoracic and cardiovascular surgery. 154(6):e125-e127 [DOI] 10.1016/j.jtcvs.2017.08.027. [PMID] 28964491.
An experimental study of the recovery of injured porcine lungs with prolonged normothermic cellularex vivolung perfusion following donation after circulatory death
Transplant International. 30(9):932-944 [DOI] 10.1111/tri.12981.
Endobronchial valve therapy for a refractory air leak after lung transplantation in a patient with multiple connective tissue disorders.
The Journal of thoracic and cardiovascular surgery. 153(1):e17-e18 [DOI] 10.1016/j.jtcvs.2016.09.069. [PMID] 27814898.
Historical perspectives of The American Association for Thoracic Surgery: Hartzell V. Schaff, MD.
The Journal of thoracic and cardiovascular surgery. 154(1):1-6 [DOI] 10.1016/j.jtcvs.2017.02.043. [PMID] 28366547.
Historical perspectives of The American Association for Thoracic Surgery: Pedro J. del Nido.
The Journal of thoracic and cardiovascular surgery. 153(2):225-227 [DOI] 10.1016/j.jtcvs.2016.10.011. [PMID] 27847163.
Impact of Postoperative Liver Dysfunction on Survival After Left Ventricular Assist Device Implantation.
The Annals of thoracic surgery. 104(5):1556-1562 [DOI] 10.1016/j.athoracsur.2017.04.048. [PMID] 28760474.
Prolonged EVLP Using OCS Lung: Cellular and Acellular Perfusates.
Transplantation. 101(10):2303-2311 [DOI] 10.1097/TP.0000000000001616. [PMID] 28009782.
Pulmonary Transplant Salvage Using Ultrasound-Assisted Thrombolysis of Subacute Occlusive Main Pulmonary Artery Embolus.
Innovations (Philadelphia, Pa.). 12(3):214-216 [DOI] 10.1097/IMI.0000000000000371. [PMID] 28538271.
Gluteal Compartment Syndrome: Successful Management with Combined Angioembolization and Surgical Decompression.
Minnesota medicine. 99(3):51-2 [PMID] 27323527.
Mitral annuloplasty ring dehiscence: Optimal force distribution with flexible rings.
The Journal of thoracic and cardiovascular surgery. 152(6) [DOI] 10.1016/j.jtcvs.2016.07.047. [PMID] 27842687.
Novel percutaneous mechanical circulatory support devices and their expanding applications.
Expert review of cardiovascular therapy. 14(10):1133-50 [DOI] 10.1080/14779072.2016.1214573. [PMID] 27450699.
Process Improvement in Thoracic Donor Organ Procurement: Implementation of a Donor Assessment Checklist.
The Annals of thoracic surgery. 102(6):1872-1877 [DOI] 10.1016/j.athoracsur.2016.06.083. [PMID] 27659600.
Strength comparison of mitral annuloplasty ring and suturing combinations: an in-vitro study.
The Journal of heart valve disease. 21(3):286-92 [PMID] 22808827.


Jun 2021 ACTIVE
Randomized Controlled Trial Comparing Dimethyl Sulfoxide Cryopreserved Platelets to Liquid Stored Platelets in Patients Undergoing Cardiopulmonary Bypass Surgery (CRYPTICS)
Role: Principal Investigator


Fellowship, Thoracic and Cardiovascular Surgery
2019-2022 · University of Florida College of Medicine
Residency, General Surgery
2013-2019 · University of Minnesota Medical School
Internship, General Surgery
2012-2013 · University of Minnesota Medical School
Medical School
2008-2012 · Medical University of South Carolina
Master's Degree, Chemistry
2007-2008 · Washington University
Bachelor's Degree, Mathematics
2003-2007 · Washington University

Contact Details

(352) 273-5501
Business Mailing:
PO Box 100129
Business Street:
1329 SW 16TH ST RM 3133